Technology & Evidence

QELBY technology and research evidence


An overview of QELBY's core technology and the bio-activity of EZ Water and Somatid — presented through CRO clinical study reports, academic papers, and patent · certification assets accumulated with 15 global universities and accredited institutes.

CRO clinical study reports5 SCI + 3 KCI papersPLOS ONE peer-reviewed

CRO clinical study overview

Study institutes · leads · study content · study type

InstituteLeadStudy contentType
Seoul National UniversityProf. Woo Hee-JongSuppression of gastric and colorectal cancer cell proliferationin vivo, in vitro
Seoul National UniversityProf. Woo Hee-JongImmunomodulatory Treg cell homeostasis regulationin vivo
KAISTProf. Lee Byung-CheonAntioxidant, tissue necrosis prevention (biophoton emission study)Lab study
Kangwon National UniversityProf. Yoon Jang-WonROS removal, mitochondrial membrane potential (MMP) increase, ATP activity, DNA damage preventionin vivo, in vitro
University of WashingtonProf. Gerald H. PollackQELBY Bio Ball & powder — EZ water structuring, negative-electron generation, plant cell growth activation (lab study)Lab study
Hankyong National UniversityProf. Hwang Seong-GuBreast cancer cell proliferation suppression, macrophage & NK cell proliferation activation, inflammatory factor (ROS) inhibitionin vivo, in vitro
Seoul Nat'l Univ. / Seegene Medical Foundation / Yonsei Care HospitalSkin-cell regeneration in long-term inpatients with pressure sores & necrosis, and diabetic foot ulcersCRO
Jeonbuk National University / Zoonotic Infectious Disease Committee Virology LabProf. Lee Sang-MyeongMaterials: mandarin Somatid, hesperidin natural gel / viral gene & protein expression inhibition, viral death, protection of infected monkey cellsin vivo

Published papers

5 SCI-indexed and 3 KCI-indexed papers · click to view

PLOS ONE peer-reviewed EZ Water

Gerald H. Pollack et al. · PLOS ONE · 2018 · Hindawi · 2017

Peer-Reviewed · PLOS ONE

3D 'cell-like' beta-zone EZ WATER formation at ambient temperature

QELBY material emits negative electrons and infrared into water without external light exposure, transmitting through glass to convert the whole body of water into EZ water in a short time under both contact and non-contact conditions.

  • 3D 'cell-like' structured water · world-first frozen-structure imaging of EZ water
  • Dielectric constant increase · Zeta potential -37.74 mV · Redox potential decrease
  • QELBY-induced increase in EZ formation and seed germination promotion (Hindawi, 2017)
Distilled water (control)
Distilled water (control)
QELBY-treated EZ water
QELBY-treated EZ water
Cryo-FE-SEM EZ water frozen microstructure grid

QELBY bio-activity characteristics

QELBY® Anti-Inflammatory Activity

Bioceramics Development and Applications (SCI), 2016 · Lee Jong-Doo · Hwang Seong-Gu · Bang Geon-Ung et al.

QELBY-treated EZ WATER increases NK cell proliferation activity by up to +43.95% and suppresses ROS and NO generation as well as key inflammatory mediators (TNF-α · IL-1β · NF-κB).

QELBY® Electrical Properties

Materials Focus (SCI) Vol.3, 2014 · Lee Jong-Doo · Atul Kulkarni · Kim Dae-Kyung · Bang Geon-Ung · Mo Sang-Hyun et al.

Strong negative-electron surface charge (Zeta potential -37.74 mV) and p-type semiconductor function, with measurable charge transport in both wet and dry states (FET analysis).

QELBY® Non-Contact Treatment Effect

Journal of Preventive Veterinary Medicine (KCI) Vol.40 No.1, 2016

Negative electrons and infrared from QELBY powder penetrate glass culture media to increase mitochondrial membrane potential (MMP), promote ATP activity, and protect DNA exposed to H₂O₂ from damage.

Antiviral Effects of Mandarin Somatid Gel

Journal of Bacteriology and Virology (JBV) Vol.51 No.4, 2021 · Prof. Lee Sang-Myeong, Jeonbuk National University

Mandarin Somatid gel above 0.625 mg/mL protected SARS-CoV-2-infected monkey (Vero E6) cells from damage and necrosis, and suppressed viral RNA replication and protein expression in a concentration-dependent manner.

QELBY experiment reports

Chart of colorectal cancer cell proliferation suppression experiment
Experiment report / CROin vivo, in vitro

Suppression of colorectal cancer cell proliferation under QELBY powder and EZ WATER conditions

Seoul National University · Prof. Woo Hee-Jong

Panel of mitochondrial membrane potential (MMP) and ATP activity experiment
Experiment report / CROin vivo, in vitro

Increased mitochondrial membrane potential (MMP) and ATP activity of QELBY-treated EZ WATER in distilled water

Kangwon National University · Prof. Yoon Jang-Won

Panel of MMP, ATP and MDH mechanism experiment
Experiment report / CROin vitro

Mechanism study of QELBY-treated EZ WATER — MMP increase and ATP activation effect

Kangwon National University · Prof. Yoon Jang-Won

Chart of Treg cell regulation experiment
Experiment report / CROin vivo, in vitro

Regulatory effect on immunomodulatory Treg cells — restoring over-active or suppressed states to normal levels

Seoul National University · Prof. Woo Hee-Jong

Comet assay image of DNA damage prevention experiment
Experiment report / CROin vitro

DNA exposed to reactive oxygen species (H₂O₂) — DNA damage prevention and ROS removal by QELBY EZ WATER treatment

Kangwon National University · Prof. Yoon Jang-Won

Cryo-FE-SEM image of EZ WATER frozen microstructure
Experiment report / CROSEM

World-first Cryo-FE-SEM imaging of the frozen microstructure of structured water (EZ WATER) in QELBY-treated distilled water

Hankyong National University · Prof. Hwang Seong-Gu

Chart of RAW 264.7 macrophage proliferation activation experiment
Experiment report / CROin vivo, in vitro

Proliferation-activation of RAW 264.7 immune macrophages by QELBY-treated distilled EZ WATER

Hankyong National University · Prof. Hwang Seong-Gu

Chart of MCF-7 breast cancer cell proliferation suppression experiment
Experiment report / CROin vivo, in vitro

Suppression of MCF-7 breast cancer cell proliferation by QELBY-treated EZ WATER

Hankyong National University · Prof. Hwang Seong-Gu

Chart of NK cell proliferation activation experiment
Experiment report / CROin vivo, in vitro

Proliferation-activation of NK cells by QELBY-treated EZ WATER

Hankyong National University · Prof. Hwang Seong-Gu

Graph of biophoton emission and tissue necrosis prevention experiment
Experiment report / CROin vitro

Biophoton emission reduction, bean-sprout stem-cell tissue necrosis prevention and antioxidant effect of EZ WATER generated in QELBY-treated distilled water

KAIST · Prof. Lee Byung-Cheon

Image of mandarin Somatid SARS-CoV-2 gene & protein expression suppression experiment
Experiment report / CROin vivo, in vitro

Suppression of SARS-CoV-2 gene & protein expression and viral death by mandarin Somatid applying plant-Somatid patent technology

Zoonotic Infectious Disease Committee Virology Lab · Prof. Lee Sang-Myeong, Jeonbuk National University

CRO treatment results

Pressure sores · foot ulcers · biological terrain (BTA)

Pressure-sore and foot-ulcer natural-gel treatment records

CRO — natural-gel treatment for pressure sores & foot ulcers

Skin-cell regeneration in long-term inpatients at a care hospital. Supervised by Prof. Woo Hee-Jong (SNU Vet. Immunology Lab) & Seegene Medical Foundation; clinical site Gangneung Yonsei Care Hospital (Director Lee Hak-Seob).

RH2 biological terrain assessment test environment

RH2 test result — biological terrain change after 20 minutes

BETA (Biological Terrain Assessment) analysis of oxidation-reduction balance in blood, urine and saliva: RH2 decreased from 27.8 to 24.1 (-13.3%) after 20 minutes, approaching the ideal balanced range (20–24).

Patents · Certifications · FDA

23 assets — patents, ISO certifications, and FDA safety-test certificates. (Papers are available in section 02 above.)

Patents

(8)

Certifications

(9)

FDA Safety Test Completed

(6)